Start to invest in research and development. Only innovation and creativity will keep you ahead of others.
Attract best human resource from the market and retain it.
Focus more on the quality of product, customers needs and wants, the bottom line will take care of itself.
https://www.quora.com/I-am-moving-from-a-startup-to-a-Fortune-100-company-in-a-senior-role-how-should-I-prepare-myself-to-survive-and-succeed/answer/Muhammad-Afsar-Malik